16th World Congress of Gynecological
Endocrinology March 5-8, 2014, Florence, Italy
On Saturday March 8, 2014 Yvette Zimmerman from Pantarhei Bioscience, lectured on the topic “The pill and androgens” in Florence. Results from a systematic review and meta-analysis evaluating the effect of combined oral contraceptives (COCs) on concentrations of total T, free T and SHBG in healthy women were presented. Based on the concept to maintain normal androgen levels in women using a COC, the natural human adrenal androgen dehydroepiandrosterone (DHEA) has been added to the contraceptive pill. This novel concept of oral contraception is referred to as Androgen Restored Contraception (ARC). The endocrine and clinical effects of ARC were evaluated in a series of clinical studies. The serious loss of androgens, especially free testosterone, was confirmed and several significant clinical effects of normalising androgens were found. Detailed results were presented during the congress.