A tumor cell specific Zona Pellucida glycoprotein 3 RNA transcript encodes an intracellular cancer antigen

Our peer-reviewed paper entitled “A tumor cell specific Zona Pellucida glycoprotein 3 RNA transcript encodes an intracellular cancer antigen” has just been published in Frontiers in Oncology!

It describes the presence and cancer-specific expression of a novel ZP3 transcript we call ‘ZP3-Cancer’ that is a highly interesting target for the development of an mRNA-based Cancer Vaccine.

Expression of ZP3-Cancer is strongly enriched in patients with ovarian cancer, colorectal cancer and in patients with a particular subtype of lung cancer. Pantarhei will strive to make a ZP3-Cancer based treatment available for patients suffering from these types of cancer.